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If the start point is already pretty skinny then not sure it is as much of an issue, but the way I see it is you are then exposed to all of the risks of glp therapy like pancreatitis or NAION, for a cosmetic result, and there may be no health benefits to offset those risks, whereas in obesity the health benefits outweigh the risks by a huge margin

R., Stenvers, D

Studies have shown combination therapy reduces recurrence significantly compared to monotherapy

doi:10.3945/ajcn.2008.26647 National Institute for Health and Care Excellence (NICE)

Association of efficacy of resistance exercise training with depressive symptoms: meta-Analysis and meta-regression analysis of randomized clinical trials