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Nowadays, FOXO4-DRI studies are focused on the following aspects: osteoarthritis (senescent chondrocyte clearance), metabolic dysfunction (insulin resistance and obesity-associated senescence), neurodegeneration (eliminating senescent brain cells), and fibrotic diseases (idiopathic pulmonary and liver fibrosis)

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Magnesium also supports GABA receptors, which promote relaxation and restful sleep

Dandge VA, Variya D

A novel approach to fat-fighting Based on this, researchers at the Tabriz University of Medical Sciences conducted a clinical trial to shed light on the promising combination of L-carnitine (a key player in glucose and lipid metabolism) and synbiotics that target gut microbiota dysbiosis as a formidable approach to tackle obesity and related cardio-metabolic complications