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glyoxalase I (Gly I) and glyoxalase II (Gly II)

It acts as one of the cell's main defences against oxidative damage - a process where unstable molecules called free radicals can harm DNA and cell structures

(31786822) pharmacology Chemical properties : Molecular weight: 163 g/mol

doi: 10.1080/10409230290771465 88 PaglianoC.SaraccoG.BarberJ

In a RDP clinical trial with 200 peri-menopausal women, a significant decrease of LDL cholesterol by 9.9% and a significant increase of HDL cholesterol by 4.6% were observed after six months of Pycnogenol (200 mg) supplementation ( supplementation by 3.9 and 3.5%, respectively, while after placebo systolic and diastolic blood pressures were decreased by 1.7 and 1%, respectively