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Research indicates that niacinamide formulations optimized at neutral pH may enhance efficacy in darker skin phototypes where enhanced permeation facilitates superior melanin transfer inhibition, making it particularly suitable for Indian dermatological practice where melasma prevalence ranges from 8-40% in certain populations

However, they might cause side effects, like itching, swelling, redness, peeling, and infection

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The proposal also hands the State Board of Pharmacy explicit inspection authority and sets penalties that include a $1,000 fine per dose and possible license revocation for violations, according to Legislative Information

But, there are other skincare options that can help with hyperpigmentation safely