Alternatively, PGC-1 may mediate the expression of motor proteins in spinal cord motoneurons and thus modulate movement disorders in an animal model of PD through the stimulation of the upstream promoter of the mitochondrial fusion-associated protein Mfn2 (Mou et al., 2021
CHAC1 expression is induced in response to various stresses, including oxidative stress, amino acid deprivation, and viral infection
Kacem O, Harzallah M, Zedini C, Zidi I, Meddeb S, Fekih M, Saidi H, Chaib A, Boughizane S, Ali HB, et al
In addition, in RP conditions the redox system is disturbed and as such for all postnatal days the [GSH]/[GSSG] ratio is sensitive to elements that govern the enzymatic reaction in which GSH reduces ROS
Consulting with a healthcare provider can help mitigate these risks