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Also, the mapping approach for transcriptomic data is based on the inclusion of highly transcribed genes and therefore is biased towards more abundant proteins, hence potentially missing lowly abundant proteins relevant for viral replication

Introduction Vitamin B12 (cobalamin) deficiency is prevalent in the elderly, with estimates indicating that approximately 20% of individuals aged 60 and over, and 23-35% of those aged 80 and above, are affected

In mitochondria, inhibition of ATP formation or electron flow through cytochrome b stimulates O2- formation by complex I and by ubiquinone (Elstner, 1991)