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Corcoy, R., Balsells, M., Garca-Patterson, A., Shmueli, A

Non-diabetic patients prescribed semaglutide have an increased likelihood of delayed gastric emptying and gallstones compared to those on other weight loss medications

The antioxidant resveratrol acts as a non-selective adenosine receptor agonist

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For weight management , certain GLP-1 formulations (liraglutide 3.0mg [Saxenda] and semaglutide 2.4mg [Wegovy]) are licensed for chronic weight management in adults with: BMI 30 kg/m , or BMI 27 kg/m with at least one weight-related comorbidity (such as type 2 diabetes, hypertension, or dyslipidaemia) However, NHS access to these medications for weight management is typically restricted to specialist tier 3 or tier 4 weight management services, with specific eligibility criteria defined by NICE technology appraisals (TA494 for liraglutide, TA664 for semaglutide) and local commissioning arrangements