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Future work will use longitudinal profiling and single-cell sequencing to assess cell-type-specific GSH roles 5 Conclusion In conclusion, by leveraging multi-omics integration, the present study identified GSH metabolism as a pivotal node in SAE, while providing a comprehensive molecular framework for SAE pathogenesis, and linking microglia-driven neuroinflammation to hippocampal oxidative damage
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The selenol is oxidized to selenenic acid by hydroperoxides, which then undergoes a reaction with GSH to form a selenenyl sulfide adduct
Pain Research and Management
Yusri, K., Kumar, S., Fong, S., Gruber, J
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