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Furthermore, earlier trials of bimagrumab showed that weight and fat loss were maintained for 12 weeks after patients stopped treatment

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Retatrutide shows particular benefit for patients with Type 2 diabetes

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moreover, it has been reported that GLP-1RA down-regulated AT1 and up-regulated AT2 in cardiomyocytes, glomerular capillaries and proximal tubules of the renal cortex in rats (73, 74, 77), resulting in a protective effect against ANG II-induced cardiac and kidney fibrosis (73, 74, 77)