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Another network meta-analysis indicated that rifaximin is associated with significant improvement in CHE, supporting the role of rifaximin as an effective therapeutic option in the early stages of the disease [123]

This recognition initiates downstream signaling cascades, amplifying a localized microbial imbalance into a systemic inflammatory state 143

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Michailov Y, Lunenfeld E, Kapilushnik J et al (2019) Acute Myeloid Leukemia Affects Mouse Sperm Parameters, Spontaneous Acrosome Reaction, and Fertility Capacity

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