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This can lead to increased drug exposure and heightened risk of adverse effects, particularly with narrow therapeutic index drugs like dabigatran [141]

Ghrelin acts on reward-related pathways by stimulating dopamine neurons in the ventral tegmental area and promoting dopamine turnover in the nucleus accumbens, a region of the ventral striatum (Xerfan et al., 2026), implicating that the anti-inflammatory properties of GLP-1 RAs could also be beneficial

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