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Cao, J., Yu, Z., Liu, W., Zhao, J., Zhang, H., Zhai, Q., & Chen, W

Journal of Pain Research, 12 , 31473159

While MRS indices are indirect measures of tissue metabolite concentrations [74], given the evidence that oral NAC administration in patients with schizophrenia increases GSH content in the ACC [69], we consider MRS as a viable tool for translational investigations into the redox abnormalities of schizophrenia

Int J Mol Sci 2009;10(9):4066-4087

In addition, because of the imbalance of electrical exchange, the cell interior is negatively charged (35 mV) compared with the exterior, favouring uptake of positively charged ions and excretion of those with a negative charge