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B12 is present in supplements and foods that have been fortified, making them potentially easier to absorb

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However, the efficacy of nasal sprays may vary compared to injectable or oral methods

Always perform a patch test on your inner arm 24 hours before applying it to your scalp

The water-soluble nature of B12 means several things for patients : the vitamin requires regular dietary intake to maintain optimal levels, it can be lost during food preparation (particularly with prolonged cooking or boiling), and therapeutic doses are generally considered safe as excess is eliminated through the kidneys, though the body's substantial hepatic storage also plays a role in B12 metabolism