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The efficacy of APAP is dose-dependent, which is affected by the PK in the different age groups

PEGylation is the covalent conjugation of polyethylene glycol (PEG) polymer to a target molecule and enhances that molecules delivery to its potential target

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It has resulted in the proposal of the Glutathione Deficiency Hypothesis , which suggests that glutathione deficiency is a primary cause of biological aging