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About 40-50,000 patients receive GLP-1 receptor agonists or sodium-glucose cotransporter-2 inhibitors(SGLT-2i) drugs, 84,000 were treated with dipeptidyl peptidase-4 (DPP-4) and more than 200,000 received sulfonylureas, with tracking of major adverse outcomes of all-cause mortality, heart attack, stroke, need for coronary revascularization

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Protein kinase C (PKC) participates in acetaminophen hepatotoxicity through c-jn-N-terminal kinase (JNK)-dependent and -independent signaling pathways

Database 2024:113