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The damage to the skin increases white blood cell activity in the area which then carries ink away, much like an infection or foreign object

doi: 10.3389/fimmu.2025.1711328 Received 23 September 2025 Revised 15 December 2025 Accepted 23 December 2025 Published 21 January 2026 Volume 16 - 2025 Edited by Francesco Nicoli, University of Ferrara, Italy Reviewed by Alessia Potenza, IRCCS San Raffaele Scientific Institute, Italy Craig Alan Byersdorfer, University of Minnesota Medical Center, United States Updates Copyright 2026 Ertl

While many rashes are mild and manageable at home, some can be severe and require immediate attention

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Cancer Cell 30 , 147160 (2016)