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GST conjugation activity GSTs have multiple biological roles, including cell protection against oxidative stress and several toxic molecules, and are involved in the synthesis and modification of leukotrienes and prostaglandins 1

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Persistent or severe symptoms suggest dose reduction or potential sensitivity

Reversibility The good news, and this is important, is that the kidney effects appeared reversible

The improved motor function with Dihexa treatment in the present study could be due to the activation of HGF/c-Met system with subsequent promotion of muscle nerve innervation