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The excretion and reabsorption of uric acid are important processes in uric acid metabolism, with several transport proteins, particularly URAT1, GLUT9, and ABCG2, found in the proximal tubules of the kidneys and intestines, playing a crucial role in the transmembrane transport of large-molecule urate salts and contributing significantly to the balance of serum uric acid
With cyanocobalamin or methylcobalamin, rare skin reactions (acne/rosacea) and gastrointestinal disturbances may occur
Its ability to inhibit elastase activity further supports the structural integrity of the skin by reducing elastin degeneration 3
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