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A patient of mine who used to be driven, ambitious, deeply present in her marriage says she feels fine

Activation of NF-B requires the phosphorylation and degradation of IB by ubiquitinproteosome pathway, contributing to translocation of NF-B dimer into the nucleus and the transcription of inflammatory genes, including cyclooxygenase-2, inducible nitric oxide synthase, tumor necrosis factor- (TNF-), and interleukin-6 (IL-6) (89)

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And yes, sugar gives quick energy but it can also set you up for that tired + hungry + snacky spiral later