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The life expectancy of people with Down syndrome has more than doubled from age 25 in 1983 to age 60 in 2020, which corresponds to a growing population of adults living with both this condition and dementia

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Many peptides discussed in this report (Semax, P21, PE-22-28) are valued precisely because they upregulate BDNF

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Nrf2, a redox-sensitive transcription factor, is pivotal in transcribing numerous antioxidant genes