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An initial phase 2 trial (NCT00809562) indicated that basimglurant (an mGlu5-negative allosteric modulator) was well tolerated in people with TRD, but formal results were not published

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Those with certain conditions: Milk thistle can have estrogenic effects, which may worsen hormone-sensitive conditions, including some types of breast cancer

Toll-like receptor signaling in cell proliferation and survival

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