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A narrative review on gut microbiome disturbances and microbial preparations in myalgic encephalomyelitis/chronic fatigue syndrome: implications for long COVID

Research Square Preprint2022 Jan

For instance, H 2 O 2 /O regulates protein synthesis by affecting key factors such as eIF2 and mTORC1, whereas protein folding is affected through disulfide bond formation in the endoplasmic reticulum mediated by enzymes such as PDI and ERO1A [205]

The combination of variants linked to a slightly increased risk of liver damage could add together to increase the risk more significantly