The SNAC Breakthrough: Oral Semaglutide (2015-2019) The first successful clinical translation of oral GLP-1 therapy came through Novo Nordisk's collaboration with Emisphere Technologies, which developed a novel absorption enhancer called sodium N-(8-[2-hydroxybenzoyl] amino) caprylate, or SNAC
Ikizler TA, Burrowes JD, Byham-Gray LD, Campbell KL, Carrero JJ, Chan W, et al
Bancorp Fund Services, LLC Trustee N/A Lead Market Maker Old Mission Options Optionable N/A Short Interest 37,600 shs Miscellaneous Outstanding Shares 1,930,000 Beta 0.41 The AI boom is creating opportunities across semiconductors, cloud computing, enterprise software, infrastructure, cybersecurity, and automation
On the flip side, digital health has the potential to scale low-cost, effective treatments by combining GLP-1 prescribing with tools that promote adherence and drive meaningful behavior change
Importantly, the FDA labeling for oral semaglutide (Rybelsus) indicates it can increase levothyroxine exposure by approximately 33% when taken together