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The typical composition of gut microbiota in healthy individuals primarily includes the phyla Bacteroidetes and Firmicutes , accounting for over 90% of the total bacteria, as well as Actinobacteria , Proteobacteria , and Verrucomicrobia [131]

In humans, this disorder is called "Ataxia with Vitamin E Deficiency" (AVED

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ROS and mitochondrial damage regulate FLS proliferation, invasion, and production of inflammatory factors and can affect FLS survival by affecting apoptosis, autophagy, and other processes mediated by FLS (34)

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