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In human trials, supplementation with 500 mg of turmeric capsules containing 22.1 mg of curcumin, administered three times daily for eight weeks, produced significant reductions in serum TGF- and IL-8 levels, and proteinuria in patients with T2DM nephropathy

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In patients with locally advanced, metastatic, and/or refractory solid tumors and hematological malignancies, CB839 is being evaluated in open-label phase I clinical trials (NCT02071862, NCT02071888, NCT02771626)

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