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After the accumulated fat is broken down, it activates the fatty acids towards the bloodstream, adapting to them and moving them to the area of the cell where fat is transformed into energy

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Additional survival and transcriptional signalling

Residence time is defined by the rate of dissociation from the receptor (1/ k off ), so we used time-resolved Forster resonance energy transfer (TR-FRET) to measure agonist-binding kinetics in CHO-SNAP-GLP-1R cells