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One of the most important function of GLP-1 is to act as an incretin by stimulating glucose-dependent release of insulin from pancreatic -cells 3,4,5 while suppressing glucagon secretion by -cells 6 , in response to food ingestion

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Interrelationship among insulin, glucagon and somatostatin secretory responses to exendin-4 in the perfused rat pancreas

Adjustmentswhether to dose timing, meal composition, or hydration targetsare straightforward and often resolve the symptom without discontinuing therapy

Morgan Research noting an 8% reduction in at-home food consumption among GLP-1 users over a 12-month period