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6 Structure Tirzepatide is a synthetic linear peptide, serves as a distinctive agonist for GIP/GLP-1 receptors, fashioned from the native sequences of GIP, GLP-1, and semaglutide, with the incorporation of distinct residues [44]

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Abstract Glucose-dependent insulinotropic polypeptide (GIP) is an intestinal hormone that potentiates glucose-induced insulin secretion in the postprandial state

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