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We further tested the in vivo therapeutic effect of JMF4073 in WT-Bcr-Abl-CML mice

A baseline DEXA, repeated every three to six months on therapy

This was a randomized controlled trial of semaglutide for alcohol use disorder that included 48 non-treatment-seeking adults with alcohol use disorder, to test semaglutides effects on alcohol craving and consumption

Levels of AST, ALT, creatinine, and oxidative stress markers including TBARS, SOD, CAT, GPx, TAS, TOS, GSH, and GSSG, along with pro-inflammatory cytokines IL-1, IL-6, IL-8, IL-10, IL-17, and TNF-, were measured using ELISA kits

-Average weight loss of 16.6% at the 25mg dose at 64 weeks