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Furthermore, impaired leptin regulation in the liver disrupts satiety signals, leading to overeating and creating a vicious cycle

We will monitor your progress and any potential side effects closely to ensure that your treatment is both safe and effective

Rapid decreases can affect the hypothalamic-pituitary-ovarian axis [12] [13] Changes in body fat percentage : Particularly relevant when body fat drops below certain thresholds Caloric restriction effects : Even with adequate nutrition, significant energy deficits can temporarily suppress reproductive function Metabolic adaptation : The body may prioritise essential functions over reproduction during periods of rapid metabolic change For women taking GLP-1 medications , the weight loss achieved may be more rapid than with lifestyle changes alone, potentially increasing the likelihood of temporary menstrual disruption

Smith, 2023)

Athauda D, Evans J, Wernick A, Virdi G, Choi ML, Lawton M, et al