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Maintaining intestinal barrier integrity is therefore essential to prevent LPS translocation and limit disease progression (53)

While some research suggests a connection between B12 levels and weight management, its role is not fully understood and it works best when paired with a healthy diet and active lifestyle

Therefore, drugs with anti-oxidant activity can be used in the treatment of MASLD

This may limit the degradation of biological components, such as proteins, DNA and lipids, crucial for membrane integrity, as indicated by markers such as 8-Hydroxy-2-deoxyguanosine (8-OHDG), AMPK activation, and modulation of several other key factors

At 3.5 hours (Fig