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The FDA prescribing information for semaglutide-based medications includes a boxed warning regarding the potential risk of thyroid C-cell tumors (medullary thyroid carcinoma, or MTC) observed in rodent studies, though human relevance has not been established

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[] These studies vary in design and outcomes, with some indicating potential benefits and others raising concerns about possible adverse effects on pregnancy

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(approximately 0.1%) ( 2 to generate significant amounts of O 2 -, the precursors to most ROS (Sohal, 1993)