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Offer alternative treatment plans When FDA-approved GLP-1s arent accessible, consider: Non-GLP-1 pharmacologic options: Bupropion-naltrexone ER (Contrave ) Phentermine-topiramate ER (Qsymia ) Orlistat Lifestyle-based programs: Structured weight management programs

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A relevant study has shown that the levels of H2Bub1 are reduced in erastin-induced ferroptosis, and the absence of H2Bub1 enhances the sensitivity of cells to ferroptosis