This review critically evaluates recent technological advances, therapeutic applications, and translational progress of microneedle (MN)-assisted delivery systems for biologics, with an emphasis on insulin, glucagon-like peptide-1 (GLP-1) receptor agonists, monoclonal antibodies, and cancer vaccines
Studies in pancreatic cells had demonstrated that GLP-1(2836) stimulates cAMP/PKA (27), a key upstream signaling pathway in pharmacological and ischemic preconditioning (28)
PMC Xie X, et al
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The results of the phase 3 trial were published on Wednesday, Sept