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That pattern is consistent with prescribing information describing gastrointestinal adverse reactions during escalation

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***Based on a 6-month clinical trial (n=180) of individuals who were enrolled between FebruaryApril 2024, with overweight or obesity taking semaglutide or tirzepatide for weight loss and related outcomes through the WW Clinic Program and participating in the GLP-1 companion nutrition program

Key Facts The agency approved changes to the drug facts label of Allis 60 mg capsules to warn of rare risks on Wednesday, including acute kidney injury, kidney stones and oxalate nephropathy, a deposit of calcium oxalate crystals into the kidney tubule that can cause kidney injury and potential fibrosis