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Administration decisions are clinician-guided

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The percentages of Cell viability and IC 50 values were calculated using the equation below 32 : Intracellular uptake and in vitro stability To assess DNZ-NLP cellular uptake and stability, SH-SY5Y cells were transfected with fluorescein isothiocyanate (FITC)-labeled DNAzyme and FITC-labeled DNZ-NLPs

Continual synthesis of endogenous glutathione is essential for normal growth and development (20), but the importance of maintaining the correct ratio of reduced:oxidised glutathione in Bd was unknown