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6) Asn-PEG8-Biotin (extended tri-LacNAc arms)
/ MUC4(1179-1194)-Tn(1183) / Mucin4
The thiol group can be reacted with other thiol-modified substrates to form disulfide bonds
Fmoc-Thr(α-D-Man(Ac)4)-OH
The C- terminus is an amide
GA230000: H-Thr(GlcNAc-β-D)-OH Pack Size:5 mg 6) Asn-PEG8-Biotin (extended tri-LacNAc arms)C12H22N2O8 322. 31 A fully unprotected (free amine, free acid) L threonine glycoamino acid carrying a D GlcNAc residue. This deprotected building block is suited to use as a reference standard, an enzymatic substrate acceptor, or for conjugation and analytical work rather than direct Fmoc SPPS. The installed glycan is O GlcNAc (GlcNAc O Ser Thr), the intracellular monosaccharide modification central to O GlcNAcylation signaling, used to build O GlcNAc
