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In a separate head-to-head comparison, GHK-Cu outperformed both retinol (vitamin A) and vitamin C in improving skin firmness and elasticity, and it did so without the irritation, photosensitivity, or adjustment period associated with retinoid use

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Key Differences It is more commonly used for skin rejuvenation and potentially for hair growth, while GHK-Cu is better known for its healing properties, anti-inflammatory effects, and use in clinical dermatology