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It functions by blocking an enzyme responsible for cellular aging and fat storage, thereby promoting improved energy metabolism, efficient fat management, and cellular rejuvenation, which can particularly benefit skin health

The histidine residue has oxidized, or the copper ion has formed insoluble complexes with degraded peptide fragments

ERK is mainly implicated in cell proliferation and Rac1 in cell migration, while p38 MAPK and JNK are involved in differentiation and apoptosis

The relatively low incidence of serious safety concerns supports the continued development and use of peptide therapeutics, although ongoing monitoring and research remain important for optimizing their clinical application

This outcome might be linked to the triggering of F-actin formation, as indicated by FITC-phalloidin staining