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According to the SmPC, the medication has a half-life of approximately one week, resulting in continuous effects on gastric emptying and gut motility throughout the dosing period, meaning gastrointestinal symptoms may occur at any time, though they are often most pronounced in the days following dose escalation

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Byetta's introduction demonstrated that synthetic GLP-1 compounds could work safely and effectively in human patients, though adoption remained limited to diabetes specialists initially

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