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Although the efficacy of tretinoin in melasma management has been established, however, a minimum treatment duration of 24 weeks is required to achieve the clinical effectiveness

Verify the finished product

Typically, these medications are introduced at a low dose and gradually increased to help the body adjust and minimise the risk of side effects such as nausea, bloating, and constipation

Starting your dose adjustment from a dehydrated, nauseated baseline is not ideal

The most effective approach starts with identifying your primary symptom, then selecting the peptide whose documented mechanism addresses that pathway directly