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13 C-NMR (100 MHz, CDCl 3 ): 196.0, 167.6, 148.7, 145.7, 132.3, 130.5, 130.3, 128.8, 127.6, 123.9, 120.9, 120.0, 118.8, 109.5, 108.2, 50.3, 48.2, 41.4, 32.2, 29.0, 27.5 ppm

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The significant reductions in renal outcomes align with evidence from cardiovascular outcome trials demonstrating additive cardiorenal benefits of combination therapy [21,22,23]

Recent studies have shown that DPP-4i can exert antihypertensive effects by interfering with the function of the RAAS system

While skin whitening injections can be effective, they may cause side effects such as redness, swelling, or allergic reactions