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In CRC, KAT8 can induce the lactylation of eEF1A2K408, leading to enhanced translational elongation and protein synthesis, thereby promoting tumorigenesis (88)

For example, certain FTO variants correlate with higher baseline weight and may influence satiety response timing, though genetics alone do not predict exact medication success

A prospective controlled study

Chovatiya R, Paller AS

Notably, seasonal variability is unlikely to fully account for the findings, as vitamin D deficiency has been shown to be prevalent across ages, sexes, and seasons in Israel (38)

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