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Experiments conducted on several animal embryogenesis models, including rodents and zebrafish, validated the transference of NPs (TiO 2 , Au, SiO 2 , carbon, and quantum dots) from mother to fetus via the placenta [127]

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Hence, targeting the cystine/cysteine metabolic system presents a viable therapeutic approach for the treatment of TNBC, as it leverages the metabolic characteristics, biomarkers and associated signaling pathways of the disease

G.MatuschewskiK.ZhangM.RugM