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In healthy individuals, these signals are transient and provoke adaptive responses, such as the upregulation of antioxidant enzymes (67)
Watanabe, F., Hashizume, E., Chan, G
To counteract this and make the drug effective for a longer time, inhibitor molecules like that in PDB entry 3gss can be administered along with the drug to inhibit the action of the enzymes
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Acetaminophen use in pregnant women and their neonates: safe or unsafe till proven otherwise
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