Nat Rev Cardiol 2010
Emerging research and clinical trial data suggest a link between semaglutide weight loss drugs and delayed gastric emptying, which may contribute to these digestive issues
In addition, these studies have also shown that taking Vitamin D3 may be able to reverse the condition (7)
Some concerning side effects mentioned include: Neurologic signs Ataxia Wobbling Seizures Gastrointestinal side effects Kidney disease concerns Possible increased rate of joint destruction The concern is that it blocks pain sensation but does not address the underlying causes
Common side effects Headache Lightheadedness Drowsiness Constipation Diarrhea Fatigue Serious side effects Allergic reaction (hives, swelling, breathing difficulty) Blurred or temporary vision loss Increased risk of heart rhythm problems Serotonin syndrome (when combined with other serotonergic drugs): agitation, rapid heart rate, fever, tremor, seizures Abnormal heart rhythm (QT prolongation): chest pain, dizziness, fainting, especially with electrolyte imbalances Masked signs of bowel obstruction after surgery or chemotherapy Risk in phenylketonuria with ODTs (contains aspartame) Warnings and precautions Avoid if allergic to ondansetron or other 5-HT3 antagonists Do not combine with apomorphine (risk of severe hypotension) Discuss history of long QT syndrome, heart failure, slow heart rate, liver disease, or digestive blockage Review all prescription, OTC medications, and supplements for interactions Sources Ondansetron (Rx)
