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Always follow the instructions on the bottle or your doctors advice

Rutin is a flavonoid found in various plants, has been reported to ameliorate DN by lowering plasma glucose levels and decreasing OS via the Nrf2 signaling pathway (Tian et al., 2016)

I do EOD of methyl b12 and take multi b vitamins thought out the day every day and a liquid sublingual b12 every day

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Along with oxidative stress, these abnormal molecular changes lead to impaired mitochondrial respiratory function, ATP depletion, and various destructive cellular processes, such as mitochondrial fission, mitophagy, and programmed cell death, as we discuss below