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Modulators of the p53 pathway, such as FOXO4-DRI and MDM2 inhibitors, selectively eliminate senescent cells but face challenges in clinical translation

It has been optimized and modified to achieve all the benefits with greater effect than the original IGF-1 molecule

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In rats that received pentadecapeptide BPC 157 immediately after paracetamol, we found no lesions after 25 minutes or 3 hours post-paracetamol, and only mild lesions after 24 hours ( Table 1 ) and consistently less liver enzymes and ammonium serum values ( Table 2 )

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