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The disease is caused by mutations in the GLA gene, located on the X-chromosome and encoding the enzyme -galactosidase A (-Gal A), which catalyzes the hydrolysis of globotriaosylceramide (Gb3) [4]

Preventing progression easier than reversing damage

Leucine is a key amino acid for signal transduction and an allosteric activator of GDH, which can induce the production of -ketoglutarate and prevent the accumulation of glutamate from inhibiting GLS

Another study performed in 2021 with 1239 individuals suffering from type 2 diabetes revealed that consuming 2 grams of L-carnitine supplement daily for 2 weeks promoted noticeable weight loss

The market is also seeing a rise in demand for liposomal delivery forms which originated largely from North American R&D