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Observation Period After dosing, patients remain in the clinic for at least 2 hours for monitoring of: Blood pressure Sedation, dissociation, and alertness A provider determines when the patient is safe to leave

Since the discovery of FSP1, more and more GPX4-independent ferroptosis pathways have been discovered in various physiological and pathological processes Drugs targeting GPX4-independent ferroptosis pathway may become a new direction for the treatment of diseases

252,253 For instance, BLT1-mediated neutrophil chemotaxis necessitates the activation of PI3K and ERK pathway, both of which are crucial for establishing cell polarity and facilitating directed motility